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EC number: 203-545-4 | CAS number: 108-05-4
Individual mean scores for conjunctival reddening at 24, 48 and 72 hours were 0.33, 0.33 and 0.33. the overall mean was therefore 0.33. There were no effects in the cornea or iris and no chemosis at 24, 48 or 72 hours in any animals.
The primary eye irritation potential of VINYLACETATE (STAB.) was investigated according to OECD test guideline no. 405. The test item was applied by instillation of 0.1 mL into the left eye of each of three young adult New Zealand White rabbits. Irritation effects were scored at approximately 1, 24, 48 and 72 hours after test item application. The instillation of VINYLACETATE (STAB.) into the eye resulted in mild, early-onset and transient ocular changes, such as reddening of the conjunctivae and sclerae, discharge and chemosis at 1 hour. However at 24 hours, there were no corneal or iridial effects and no chemosis in any animals. Slight conjunctival reddening was present in all 3 animals at 24 hours but was not present at 48 hours.
The overall mean score for conjunctival reddening was 0.33 and based upon the referred classification criteria (Commission Directive 2001/59/EC of August 06. 2001), VINYLACETATE (STAB) is considered to be "not irritating" to the rabbit eye.
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