Acrylamide

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

unkown

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Handbook data

Data source

Reference

Reference 1

Reference Type:

review article or handbook

Title:

Acrylamide: It's preparation and properties

Author:

Carpenter, EL and Davis, HS

Year:

1957

Bibliographic source:

J. Appl. Chem. 7, 671 - 676

Reference 2

Reference Type:

secondary source

Title:

Unnamed

Year:

2002

Materials and methods

Test guideline

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

GLP compliance:

no

Remarks:

Pre-GLP

Type of method:

gas saturation method

Test material

Test material information

Constituent 1

Reference substance name:

Acrylamide

EC Number:

201-173-7

EC Name:

Acrylamide

Cas Number:

79-06-1

Molecular formula:

C3H5NO

IUPAC Name:

prop-2-enamide

Results and discussion

Vapour pressure

Vapour pressure 1

Temp.:

25 °C

Vapour pressure:

0.9 Pa

Vapour pressure 2

Temp.:

40 °C

Vapour pressure:

4.4 Pa

Vapour pressure 3

Temp.:

50 °C

Vapour pressure:

11 Pa

Vapour pressure 4

Temp.:

85 °C

Vapour pressure:

230 Pa

Applicant's summary and conclusion

Conclusions:

Solid acrylamide sublimes near its melting point (85°C) with a vapour pressure of 230 Pa. The vapour pressure of acrylamide solutions (50%) at 25°C is < 2.5 kPa, the partial vapour pressure of acrylamide above the solution is 2.3 Pa and the vapour concentration of acrylamide in a saturated atmosphere above an aqueous solution is approximately 0.0003% (3ppm).