Registration Dossier
Registration Dossier
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EC number: 289-339-5 | CAS number: 87741-01-3
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Type of information:
- other: EU Risk Assessment
- Adequacy of study:
- other information
- Reliability:
- other:
Data source
Reference
- Reference Type:
- other: EU Risk Assessment
- Title:
- European Union Risk Assessment Report 1,3-BUTADIENE, CAS No: 106-99-0, EINECS No:203-450-8
- Author:
- [ECB] European Chemicals Bureau
- Year:
- 2 002
Materials and methods
- Principles of method if other than guideline:
- EU Risk Assessment on the major component of C4 Hydrocarbons: 1,3-Butadiene
Test material
- Reference substance name:
- Buta-1,3-diene
- EC Number:
- 203-450-8
- EC Name:
- Buta-1,3-diene
- Cas Number:
- 106-99-0
- Molecular formula:
- C4H6
- IUPAC Name:
- buta-1,3-diene
- Details on test material:
- - Name of test material (as cited in study report): 1,3-butadiene
1,3-butadiene is the major and toxicologically most relevant component of C4-Hydrocarbons
(see attached document 'Read Across C4 Hydrocarbons' under chapter 13).
Constituent 1
Results and discussion
Any other information on results incl. tables
There are no data on the skin or respiratory sensitisation potential of butadiene in animals.
However, the gaseous nature of butadiene precludes the conduct of conventional skin sensitisation tests in animals.
Applicant's summary and conclusion
- Executive summary:
There are no data on the skin or respiratory sensitisation potential of butadiene in animals.
However, the gaseous nature of butadiene precludes the conduct of conventional skin sensitisation tests in animals.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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