Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

eye irritation: in vitro / ex vivo
Data waiving:
other justification
Justification for data waiving:

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion

Executive summary:

Silicon carbide (crude and grains) is an inert chemical and is likely to cause mechanical eye irritation due to large particle size and shape. Mechanical eye irritation produced by silicon carbide would camouflage any chemical irritation that might be caused by the substance. For this reason and due to the unethical aspect of in vivo eye irritation testing of a mechanical irritant, it was not considered reasonable to perform an eye irritation study.

In addition, documented occupational experience with the handling and use of silicon carbide (crude and grains) has revealed no cases of eye or dermal corrosion (i.e. irreversible damage to the skin or to the eye).