Registration Dossier

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

Freshwater:

From the database of chronic nickel toxicity to freshwater invertebrates, many individual EC10or NOEC values for different individual species were selected. Chronic data on invertebrates belonging to different taxonomic groups being cladoceran (79% of the data points), amphipods (0.9% of the data), insects (7% of the data), hydrozoans (0.9% of the data), rotifers (5% of the data) and a mollusc (7% of the data). The NOEC/L(E) C10 varied between 1.4 μg/L forLymnaea stagnalis(Schlekat et al., 2010) and 1,379µg/L forBrachionus calyciflorus(Schlekat et al., 2010). It is noted that the invertebrate data are heavily dominated by data on cladocerans.

 

The following table indicates those NOEC or EC10 values of high quality that have been carried forward for the HC5 & PNEC derivation:

 

Key Study

(freshwater invertebrates)

Selected values for the most sensitive endpoints used for derivation of the freshwater HC5

Species

Endpoint

Value (s) (µg/L)

Deleebeecket al., 2008

Daphnia magna

NOEC/EC10

8.8-256

Kunhet al., 1989

Daphnia magna

NOEC

90

Munzinger, 1990

Daphnia magna

NOEC

40

Munzinger, 1994

Daphnia magna

NOEC

80

Keithlyet al., 2004

Ceriodaphnia dubia

NOEC

3.4-5.8

Wirtzet al., 2004

Ceriodaphnia dubia

EC10

2.8-7.6

Deleebeecket al., 2009b

Ceriodaphnia dubia

EC10

7.4-44.2

Nebekeret al., 1984

Clistorina magnifica

NOEC

66

Nebekeret al., 1986

Juga plicifera

NOEC

124

Santiago-Fandino, 1983

Hydra littoralis

NOEC

60

Keithlyet al., 2004

Hyalella azteca

NOEC

29

Deleebeecket al., 2006

Ceriodaphnia quadrangula

NOEC

2.0-12.7

Peracantha truncata

NOEC

2.5-25.8

Daphnia longispina

NOEC

26.6-29.0

Alona affinis

NOEC

25.0

Ceriodaphnia pulchella

NOEC

9.9-28.2

Simocephalus vetulus

NOEC

9.2-28.9

 

Schlekat et al., 2010

Lymnaea stagnalis

EC10

1.4 -19.5

Brachionus calyciflorus

EC10

498-1379

Chironomus tentans

EC10

404-782

 

Marine:

From the database of chronic nickel toxicity to marine invertebrates, many NOEC/EC10/LOEC values are reported. EC10values range from 22.5 μg Ni/L for reproduction of the polychaete,Neanthes arenaceodentata(DeForest and Schlekat, 2013), to 431 μg Ni/L for development of the bivalve,Crassostrea gigas(DeForest and Schlekat, 2013). The table below represents the NOEC, LOEC, or EC10values of high quality carried forward for derivation of HC5and aquatic marine PNEC:

 

Key Study

(marine invertebrates)

Selected values for the most sensitive endpoints used for derivation of the marine HC5

Species

Endpoint

Value (s) (µg/L)

 DeForest and Schlekat, 2013

Strongylocentrotus purpuratus

EC10

335

Dendraster excentricus

EC10

191

Huntet al., 2002

Mysidopsis intii

EC10

45.2

Haliotis rufescens

EC10

36.4

Gentileet al., 1982

Mysidopsis bahia

LOEC

141

Mysidopsis bahia

NOEC

 61

 DeForest and Schlekat, 2013

Mytilius galloprovincialis

EC10

269.7 (geomean)

 DeForest and Schlekat, 2013

Neanthes arenaceodentata

EC10

22.5

 DeForest and Schlekat, 2013

Crassostrea gigas

EC10

431

Novelliet al., 2003

Paracentrotus lividus

EC10

89

Pagano, 2007

Paracentrotus lividus

EC10

217