Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

EC 50: 20000 mg/L
IC50: 880 - >1000 mg/L
toxic treshold values: 530 - 6600 mg/L

Key value for chemical safety assessment

EC50 for microorganisms:
20 000 mg/L

Additional information

Bringmann and Kuehn (1978) determined a toxic treshold value (TGK) of 530 mg/L in a 192h test with Microcystis aeruginosa. The same authors report a further toxic treshold value resulting from a cell multiplication test for 16 hours, using two Pseudomonas species, at 6600 mg/L (Bringmann and Kuehn 1977). Other test results reported are an EC50 of 20000 mg/L for activated sluge and an IC50 value of 880 mg/L for Nitrosamonas (Blum and Speece 1991). An IC50 value >1000 mg/L for activated sludge is reported by Klecka et al. (1985). This test was performed according to the OECD Guideline 209 (activated sludge, respiration inhibition test) and is considered the most appropriate for assessing the risk for wastewater treatment plant.