Registration Dossier
Registration Dossier
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EC number: 431-850-4 | CAS number: 7456-68-0
Eye irritation
Administrative data
- Endpoint:
- eye irritation
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 92/69/EWG, B.5; OECD 405
- GLP compliance:
- yes
Test material
- Reference substance name:
- Automatically generated during migration to IUCLID 6, no data available
- IUPAC Name:
- Automatically generated during migration to IUCLID 6, no data available
- Details on test material:
- Nature of substance: Feststoff (solid)
Constituent 1
Test animals / tissue source
- Species:
- other: rbt, New Zealand White
Test system
- Amount / concentration applied:
- CA 100 MG
- Number of animals or in vitro replicates:
- 6
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- conjunctivae score
- Remarks:
- (redness)
- Basis:
- mean
- Score:
- 0.67
- Max. score:
- 1
- Remarks on result:
- other: Max. duration: 3 h; Max. value at end of observation period: 0
- Irritation parameter:
- chemosis score
- Basis:
- mean
- Score:
- 0.28
- Max. score:
- 2
- Remarks on result:
- other: Max. duration: 2 h; Max. value at end of observation period: 0
- Irritation parameter:
- cornea opacity score
- Basis:
- mean
- Score:
- 0
- Max. score:
- 0
- Remarks on result:
- other: Max. duration: 0 h; Max. value at end of observation period: 0
- Irritation parameter:
- iris score
- Basis:
- mean
- Score:
- 0.06
- Max. score:
- 1
- Remarks on result:
- other: Max. duration: 2 h; Max. value at end of observation period: 0
- Irritant / corrosive response data:
- Reversibility of any observed effect: Changes fully reversible within 3 days
- Other effects:
- Der Austritt in alle Kaninchen war verschwunden 24 Stunden
nach Applikation.
"ENGLISH"
The discharge has resolved in all rabbits 24 hours after
dosing.
Applicant's summary and conclusion
- Interpretation of results:
- other: not classified
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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