Registration Dossier
Registration Dossier
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EC number: 205-480-7 | CAS number: 141-32-2
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
n-Butyl acrylate is acutely toxic to freshwater invertebrates.
EC50 (48 h) = 8.2 mg/L (measured), (Daphnia magna, OECD TG 202, flow through)
Key value for chemical safety assessment
Additional information
The acute toxicity study with Daphnia magna (BAMM, 1990) resulted in a 48 -hour EC50 of 8.2 mg/L based on mean measured concentrations. This study followed OECD TG 202, part I using a flow-through design. Nominal exposure concentrations ranged from 1.2 to 20 mg/L and mean measured concentrations ranged from 1.4 to 17 mg/L. Complete immobilization occurred in the highest concentration (17 mg/L, measured). The NOEC was 2.4 mg/L (measured).
In short-term tests with Daphnia magna conducted according to a draft version of the German standard guideline DIN 38412 L11, 24-hour EC50 values of 42 and 230 mg/L, respectively, were found (Bringmann & Kuehn 1977, 1982). The given effect values were related to nominal concentrations.
Since BA is readily biodegradable and moderately volatile, only test results from studies with analytical monitoring were used for the hazard assessment for freshwater invertebrates.
In addition, a robust data set of acute studies is available from the other members of the acrylic ester category (methyl, 2-ethylhexyl, ethyl, isobutyl and tert-butyl acrylate).
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