Registration Dossier
Registration Dossier
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EC number: 264-513-3 | CAS number: 63843-89-0
Dermal absorption
Administrative data
- Endpoint:
- dermal absorption
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2013
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: well-performed non-guideline study, non-GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
- Principles of method if other than guideline:
- Solubility in artificial perspiration fluid
- GLP compliance:
- no
Test material
- Reference substance name:
- Bis(1,2,2,6,6-pentamethyl-4-piperidyl) [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]butylmalonate
- EC Number:
- 264-513-3
- EC Name:
- Bis(1,2,2,6,6-pentamethyl-4-piperidyl) [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]butylmalonate
- Cas Number:
- 63843-89-0
- Molecular formula:
- C42H72N2O5
- IUPAC Name:
- bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-butyl-2-[(3,5-di-tert-butyl-4-hydroxyphenyl)methyl]propanedioate
- Details on test material:
- batch no. 0005039980
Purity: 98%
Constituent 1
- Radiolabelling:
- no
Results and discussion
Applicant's summary and conclusion
- Executive summary:
The solubility in artificial perspiration fluid at 37 °C after 1h, 2h, 4h and 24h of stirring was 16 mg/L.
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