Inositol phosphates

Surface tension

Administrative data

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From April 07, 2009 to May 13, 2009

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

The study was conducted according to EU Method A.5 (Surface Tension). GLP compliance is claimed through compliance with UK Good Laboratory Practice standards [Schedule 1, Good Laboratory Practice Regulations 1999 (SI 1999/3106 as amended by SI 2004/0994)].

Justification for data waiving:

other:

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to same study

Cross-reference 2

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2009

Report date:

2009

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Deviations:

yes

Remarks:

The surface tension result was not corrected using the Harkins-Jordan correction table as the correction is not applicable to the apparatus used.

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Type of method:

ring method

Test material

Test material information

Constituent 1

Reference substance name:

Inositol phosphates

EC Number:

700-206-7

Molecular formula:

As this substance is a UVCB substance and consists varying degree of components, a single molecular formula is not applicable

IUPAC Name:

Inositol phosphates

Constituent 2

Reference substance name:

Synthetic inositol phosphates

IUPAC Name:

Synthetic inositol phosphates

Details on test material:

- Name of test material (as cited in study report): Synthetic Inositol phosphates
- Physical state: Amber coloured liquid
- Lot/batch No.: 95816206JH-012
- Storage condition of test material: Room temperature in the dark

Results and discussion

Surface tension

Surface tension:

72.6 mN/m

Temp.:

21 °C

Conc.:

4.25 g/L

Any other information on results incl. tables

Table 1: Readings, temperatures and the corresponding calibration factors for glass double-distilled water

 

Reading (mN/m)	Temperature (°C)	Literature value (mN/m)	Calibration factor
72.5	21.0	72.6	1.001
72.5	21.0	72.6	1.001
72.5	21.0	72.6	1.001
72.5	21.0	72.6	1.001
72.5	21.0	72.6	1.001
72.5	21.0	72.6	1.001
Mean Calibration factor = 1.001

 

Table 2: Readings, times and temperatures for the sample solution

 

Time (mins)	Reading (mN/m)	Temperature (°C)
60	72.5	21 °C
70	72.5	21 °C
80	72.5	21 °C
90	72.5	21 °C
95	72.5	21 °C

 

Mean reading: 72.5 mN/m

Surface tension = reading x calibration factor = 72.5 X1.001 = 72.6 mN/m

Temperature = 21.0 ± 0.5 °C

pH of sample solution = 2.1

Applicant's summary and conclusion

Conclusions:

The surface tension of the test material solution (4.25 g/L) was determined to be 72.6 mN/m at 21.0 ± 0.5°C. The test material was considered not to be a surface-active material.

Executive summary:

A study was conducted to determine the surface tension of synthetic inositol phosphates based on ISO 304 ring method, EU Method A.5 (Surface Tension). 

The test material solution (4.25 g/L) was transferred to the measuring vessel and the minimum force required for detaching the ring from the surface of the liquid was recorded.

 

The surface tension of the test material solution (4.25 g/L) was determined to be 72.6 mN/m at 21.0 ± 0.5°C. The test material was considered not to be a surface-active material.