Registration Dossier
Registration Dossier
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EC number: 237-222-4 | CAS number: 13701-59-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Based on the results of the available fish acute studies Oncorhynchus mykiss were the most sensitive, an LC50 of 62 mg a.i./L and a
NOEC of 25.6 mg a.i./L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 62 mg/L
Additional information
Acute fish toxicity studies are available for both rainbow trout (Oncorhynchus mykiss) and bluegill sunfish (Lepomis macrochirus).
A 96 -hour GLP static acute fish test with Oncorhynchus mykiss was conducted in accordance with the USEPA 72-1 Fish Pesticide Acute Toxicity Test Guideline at nominal concentrations of 26, 43, 72, 120 and 200 mg a.i./L.
Survival of fish was monitored daily and any dead fish removed. Any abnormalities in the behaviour or physical appearance of the fish were also noted. The 96-hour LC50 based on mean measured concentrations was 62 mg ai/L with 95 percent confidence limits of 47.0 and 84.5 mg ai/L. The no-observed-effect concentration (NOEC) was determined to be 25.6 mg ai/L.
The 96-hour fish acute test with Bluegill sunfish (Lepomis macrochirus) was conducted in accordance with USEPA 72-1 Fish Pesticide Acute Toxicity Test Guideline at nominal concentrations of 26, 43, 72, 120 and 200 mg a.i./L.
The 96-hour LC50 based on mean measured concentrations was 151 mg ai/L with 95 percent confidence limits of 112 and 299 mg ai/L. The no-observed-effect concentration (NOEC) was determined to be 42.8 mg ai/L.
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