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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

No effects up to the limit of water solubility.

Key value for chemical safety assessment

Additional information

In general, no intrinsic effects among the members of the SCAE C2 -8 category towards algae were observed. All EC/EL50(72h) values were above the limit of water solubility.

No studies on toxicity to algae are available for Isopropyl palmitate

 In the key study, a read-across from the substance Isopropyl myristate (CAS 110-27-0), Desmodesmus subspicatus was tested according to EU Method C.3 and to GLP as a limit test (Rieche 1995). No effects on cell growth were stated at concentrations above the water solubility (ErC50 > 0.05 mg/L) in the filtered emulsion of the test medium, while presumably physical effects were observed in the emulsion without filtration (ErC50 < 100 mg/L, nominal).

In a supporting study, a read-across from Fatty acids, C16-C18 and C18 unsatd., branched and linear, Bu esters (CAS 163961-32-8), Desmodesmus subspicatus was tested under static conditions according to OECD 201 as limit test under GLP conditions (Hudson 2004). The tested concentration of 0.2 mg/L (nominal) was applied in a solvent-spike method (with acetone). The analytical measurement of the test substance resulted in an arithmetical mean of 0.054 mg/L, resulting in an EC50(72h) value of >0.054 mg/L and a NOEC(72h) of 0.054 mg/L (cell number).


As another supporting study, a read across from, Fatty acids, C16-18 and C18-unsatd., 2-ethylhexyl esters (CAS: 85049-37-2) was used. In this test, the marine alga Skeletonema costatum was tested with WAF according to ISO 10253. The resulting ErL50(72h) was determined as 281.4 mg/L (nominal)(Vryenhoef and McKenzie 2000).