A mixture of: N-(4-chlorophenyl)-4-(2,5-dichloro-4-(dimethylsulfamoyl)phenylazo)-3-hydroxy-2-naphthalenecarboxamide; N-(4-chlorophenyl)-4-(2,5-dichloro-4-(methylsulfamoyl)phenylazo)-3-hydroxy-2-naphthalenecarboxamide

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:

solubility in organic solvents / fat solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1993

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: vaild method (restrictions for low solubility substances)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1993

Report date:

1993

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: EEC Directive 84/449 (1984) - Methode A7

Deviations:

no

GLP compliance:

yes

Test material

Test material information

Constituent 1

Results and discussion

Solubility in organic solvents / fat solubility

Medium:

other: copra oil (batch n° 41HO182, Sigma)

Solubility:

0 other: g/100 g fat

Temp.:

37 °C

Test substance stable:

not determined

Applicant's summary and conclusion

Conclusions:

Solubility in fat was very low whatever parameter (temperature or stirring time) was modified and no significant differences were observed between the results. Under the experimental conditions described, the fat solubility was estimated to be 1.92 x 10-4 g/100 g fat at 37°C.