Registration Dossier
Registration Dossier
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EC number: 931-254-9 | CAS number: 64742-49-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
There is no data available for this substance. However, key and supporting data is available for the structural analogues Hydrocarbons, C6-C7, isoalkanes, cyclics, <5% n-hexane and Hexane. The data is read across to this substance based on analogue read across and a discussion and report on the read across strategy is provided as an attachment in IUCLID Section 13.
Hydrocarbons, C6-C7, isoalkanes, cyclics, <5% n-hexane presented a 72-h ErL50 of 55 mg/L, a 72-h EbL50 of 26 mg/L and a 72-h NOEL of 30 mg/L for Raphidocelis subcapitata based on growth rate.
Hexane presented a 10-d EC50 (growth rate) for Chlorella pyrenoidosa of 2.66% v/v of test substance.
Key value for chemical safety assessment
Additional information
Two study reports were available and input as endpoint records. The studies were scientifically reliable according to Klimish (Klimish et al., 1997) scoring (Klimish 1 and 2).
The study from Shell (1994) examined the short-term toxicity of the test substance SBP 60/95 LNH (Hydrocarbons, C6-C7, isoalkanes, cyclics, <5% n-hexane) to Raphidocelis subcapitata. Cultures of R. subcapitata were exposed to concentrations of 0, 1.0, 3.0, 10, 30, 100, 300, and 1000 mg/L of test substance. The growth of the algae was then measured at 0, 24, 48, and 72 h and compared to controls. The ErL50 at 72 h was 55 mg/L, the EbL50 at 72-h was 26 mg/L and the NOEL was calculated to be 30 mg/L based on growth rate.
The study from Stratton and Smith (1988) examined the toxicity of n-hexane to green algae. The green algae C. pyreniodosa was exposed to concentrations of test substance varying between 1.0 - 14 % v/v. The exposure lasted for 10 -14 days. The growth rate and cell count was monitored. Results showed an EC50 of 2.66% v/v of test substance.
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