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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
Not reported
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original study not available, information obtained from a summary within an IUCLID Data Set. The authors of the dataset assigned the original source a reliability score of 4. Intraperitoneal is not a toxicologically relevant route of exposure.

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Unnamed
Year:
2006
Report date:
2006
Reference Type:
study report
Title:
Unnamed
Year:
1992
Report date:
1992

Materials and methods

Principles of method if other than guideline:
No information relating to materials and methods reported, only the lethal dose value was reported. The information was presented as a summary as part of an IUCLID data set.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Dioctyltin oxide
EC Number:
212-791-1
EC Name:
Dioctyltin oxide
Cas Number:
870-08-6
Molecular formula:
C16H34OSn
IUPAC Name:
dioctylstannanone
Test material form:
not specified
Details on test material:
- Name of test material (as cited in study report): Dioctyltin oxide

Test animals

Species:
mouse
Strain:
not specified
Sex:
male/female

Administration / exposure

Route of administration:
intraperitoneal

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
370 - 400 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Conclusions:
The LD50 in male and female mice of the test substance via the intraperitoneal route was reported to be 370-400 mg/kg bw.
Executive summary:

No information relating to materials and methods reported, only the lethal dose value was reported. The information was presented as a summary as part of an IUCLID data set. The LD50 in male and female mice of the test substance via the intraperitoneal route was reported to be 370-400 mg/kg bw.