Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

The subacute application of the test substance to rats did not result in any toxic effects. 

Key value for chemical safety assessment

Repeated dose toxicity: via oral route - systemic effects

Endpoint conclusion
Dose descriptor:
NOAEL
200 mg/kg bw/day
Study duration:
subacute
Species:
rat

Additional information

The test substance was applied orally to rats for 28 days in doses up to 1000 mg/kg bw. Minor signs of toxicity were detected in high-dosed animals. Based upon these results, the NOAEL 200 mg/kg body weight for male and female rats when administered

orally by gavage for a period of 28 days.

Dose selection was based on a 5-days range-finding study in rats where no toxic effects were observed.

The studies were found to be adequate to fufill the purposes of this endpoint.

Justification for classification or non-classification

There are conclusive but not sufficient data for classification of the test substance with regard to repeated dose toxicity in accordance to Directive 67/548/EEC or target organ toxicity referring to the CLP Regulation (EC) No 1272/2008.

The substance is not classified for these endpoints.