Registration Dossier
Registration Dossier
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EC number: 201-056-0 | CAS number: 77-76-9
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: no GLP or OECD guidelines followed, no detailed description available
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 977
- Report date:
- 1978
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Deviations:
- not applicable
- Principles of method if other than guideline:
- 5 doses within the first 5 days followed by 10 days of observations
- GLP compliance:
- not specified
- Test type:
- other:
- Limit test:
- no
Test material
- Reference substance name:
- Acetone-dimethyl acetal
- EC Number:
- 201-056-0
- EC Name:
- Acetone-dimethyl acetal
- Cas Number:
- 77-76-9
- Molecular formula:
- C5H12O2
- IUPAC Name:
- 2,2-dimethoxypropane
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- not specified
- Doses:
- 8000, 4000, 2000, 1000 mg/kg bw
- No. of animals per sex per dose:
- 5 or 10 per dose
- Control animals:
- yes
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- >= 4 000 mg/kg bw
- Based on:
- test mat.
Any other information on results incl. tables
-
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Substance does not need to be classified as acut toxic (EU)
- Executive summary:
-
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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