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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Description of key information

BCF = 29.27 l/kg wet-wt

BCF = 1.207

BAF = 1589

Key value for chemical safety assessment

BCF (aquatic species):
29.27 L/kg ww

Additional information

The Bioconcentration and Bioaccumulation factors above, estimated by means of BCFBAF v3.01 (September 2012) have been used in order to complete the assessment.

Moreover an information on bioaccumulation in fish ("accumulation in carps was judged to be very small") on the Similar Substance 01 (CAS 21850-77-2) reported in Great Lakes Chemical Corporation (1987) [1] cited in the WHO publication[2] has been used as a supporting information for the assessment on the basis of the wide similarity between AP 1300 S and Similar Substance 01; the two chemicals share the same structure, except for the fact that Similar Substance 01 presents two dibromobutane functional groups linked to the dibromophenol core, instead the dibromo-methylbutane as in the case of AP 1300 S. The justification for the Read Across approach has been detailed in the document attached to the IUCLID Section 13.

[1] Great Lakes Chemical Corporation (1987) Summaries of toxicity data. PE-68, Bis(2,3-dibromopropyl ether) of tetrabromobisphenol A. West Lafayette, Indiana, Great Lakes Chemical Corporation (Unpublished   report submitted to WHO by the Brominated Flame Retardant Industry Panel).


[2]World Health Organization (WHO, Geneva, 1995); Dr. G.J. van Esch “Tetrabromobisphenol A and Derivatived” (Environmental health criteria ; 172)