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Administrative data

Link to relevant study record(s)

Description of key information

Single Oral administration:

elimination in the foeces: 95 % of dose by 36 h

urinary elimination: < 0.1 %

bile elimination: 1 % in 24 h

IV administration

elimination in the foeces: 27 % of dose by 36 h; 71 % of dose by 96 h

urinary elimination: < 0.1 %

Key value for chemical safety assessment

Bioaccumulation potential:
low bioaccumulation potential

Additional information

There are no data about the basic toxicokinetics of AP 1300 S, thus the available information about the structural analogous Similar Substance 01 (CAS 21850-44-2, 1,1'-propane-2,2-diylbis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene]) have been taken into account.

 

Similar Substance 01 shares with AP 1300 S the same structure, except for the fact that Similar Substance 01 presents two dibromobutane functional groups linked to the dibromophenol core, instead the dibromo-methylbutane as in the case of AP 1300 S. The justification for the Read Across approach has been detailed in the document attached to the IUCLID Section 13.