Registration Dossier
Registration Dossier
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EC number: 306-832-3 | CAS number: 97416-84-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Basic data given. The justification for the Read Across approach has been attached to the Section 13
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- AN ALTERNATIVES ASSESSMENT FOR THE FLAME RETARDANT DECABROMODIPHENYL ETHER (DecaBDE)
- Author:
- EPA United Stated Environmental Protection Agency
- Year:
- 1 994
- Bibliographic source:
- Not applicable
- Reference Type:
- secondary source
- Title:
- Not Available
- Author:
- Great Lakes ChemicalCorporation
- Year:
- 1 987
- Bibliographic source:
- Unpublished report
Materials and methods
- Principles of method if other than guideline:
- No available information on method used
- GLP compliance:
- not specified
- Test type:
- other: No available information
Test material
- Reference substance name:
- Similar Substance 01
- IUPAC Name:
- Similar Substance 01
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No available information
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Details on inhalation exposure:
- No available information
- Remarks on duration:
- No available information
- Concentrations:
- No available information
- No. of animals per sex per dose:
- No available information
- Control animals:
- not specified
- Details on study design:
- No available information
- Statistics:
- No available information
Results and discussion
Effect levelsopen allclose all
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- > 87 000 mg/m³ air
- Based on:
- not specified
- Remarks on result:
- other: No information on exposition and confidence level
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- > 87 mg/L air
- Based on:
- not specified
- Remarks on result:
- other: No information on exposition and confidence level
- Mortality:
- No available information
- Clinical signs:
- other: No available information
- Body weight:
- No available information
- Gross pathology:
- No available information
- Other findings:
- No available information
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information According to the CLP Regulation Criteria used for interpretation of results: EU
- Conclusions:
- LC50 > 87000 mg/m3
- Executive summary:
Method
The evaluation of acute inhalation toxicity reported from Greate Lakes Chemical Corporation (1982) in the WHO publication[1] has been considered in order to complete the assessment.
The test has been conducted on mouse. No further information on the method used is available.
Results
The LC50 by the inhalation route reported on the Similar Substance 01 in these reviews is greater than 87000 mg/m3 (LC50 > 87 mg/l).
[1]World Health Organization (WHO, Geneva, 1995); Dr. G.J. van Esch “Tetrabromobisphenol A and Derivatived” (Environmental health criteria; 172)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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