Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 266-046-0 | CAS number: 65997-17-3 This category encompasses the various chemical substances manufactured in the production of inorganic glasses. For purposes of this category, 'glass' is defined as an amorfous, inorganic, transparent, translucent or opaque material traditionally formed by fusion of sources of silica with a flux, such as an alkali-metal carbonate, boron oxide, etc. and a stabilizer, into a mass which is cooled to a rigid condition without crystallization in the case of transparent or liquid-phase separated glass or with controlled crystallization in the case of glass-ceramics. The category consists of the various chemical substances, other than by-products or impurities, which are formed during the production of various glasses and concurrently incorporated into a glass mixture. All glasses contain one or more of these substances, but few, if any, contain all of them. The elements listed below are principally present as components of oxide systems but some may also be present as halides or chalcogenides, in multiple oxidation states, or in more complex compounds. Trace amounts of other oxides or chemical compounds may be present. Oxides of the first seven elements listed* comprise more than 95 percent, by weight, of the glass produced. @Aluminium*@Lead@Boron*@Lithium@Calcium*@Manganese@Magnesium*@Molybdenum@Potassium*@Neodymium@Silicon*@Nickel@Sodium*@Niobium@Antimony@Nitrogen@Arsenic@Phosphorus@Barium@Praseodymium@Bismuth@Rubidium@Cadmium@Selenium@Carbon@Silver@Cerium@Strontium@Cesium@Sulfur@Chromium@Tellurium@Cobalt@Tin@Copper@Titanium@Germanium@Tungsten@Gold@Uranium@Holmium@Vanadium@Iron@Zinc@Lanthanum@Zirconium
Endpoint summary
Administrative data
Description of key information
E-glass microfibre is assessed to have no acute toxicity by ingestion, by skin contact or by inhalation. E-glass microfibre shall not be classified as an acute toxicant according to the criteria in Council Directive 67/548/EEC and Regulation (EC) 1272/2008.
Key value for chemical safety assessment
Additional information
Testing of acute oral and dermal toxicities is waived based on the fact that E-glass microfibre is inorganic and highly water insloluble. It's physicochemical properties suggest a low potential to cross biological membranes and consequently a low potential for absorption through the gastrointestinal tract and through the skin.
Study of acute inhalation toxicity is waived because results from long-term inhalation toxicity studies are available. Inhalation of E-glass microfibre is highly unlikely to induce acute toxicity. In conclusion, E-glass microfibre is assessed to have no acute toxicity by ingestion, skin contact or by inhalation.
Justification for classification or non-classification
E-glass micro fibre is inorganic. The physicochemical properties suggest a low potential to cross biological membranes. Thus, E-glass microfibre has a low potential for absorption into the body through the skin, the airways and the gastrointestinal tract.
E-glass microfibre is assessed to have no acute toxicity by skin contact or if ingested. E-glass microfibre is inorganic and is evaluated to have low potential for crossing biological membranes and that acute toxicity following inhalation is negligible. E-glass microfibre is assessed to have no acute toxicity by inhalation. In conclusion, E-glass microfibre shall not be classified as an acute toxicant according to the criteria in Council Directive 67/548/EEC and Regulation (EC) 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
