Registration Dossier

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

EC10 =31.7 mg/L, NOEC = 10 mg/L, EC50 = 594 mg/L (OECD Guideline 209 (respiration inhibition test) with activated sludge; GLP, RL1)

Key value for chemical safety assessment

EC50 for microorganisms:
594 mg/L
EC10 or NOEC for microorganisms:
31.7 mg/L

Additional information

In a 3 h respiration inhibition study, activated sludge a predominantly municipal sewage treatment plant was exposed to Epoxy half acrylate (100% a.i.) at nominal concentrations of 0 (control), 10, 32, 100, 320 and 1000 mg/L in accordance with OECD Guideline 209 (2010). Copper (II) sulphate pentahydrate at concentrations of 58, 100 and 180 mg/L was used as reference substance. The respiration rates of the control, reference and test item replicates were measured after a contact time of three hours, and the inhibitory effects of the test and reference item were determined in comparison to the control respiration rates. The mean inhibition of respiration for the test item replicates ranged from 3% to 63%.

The 3 h EC50 was determined to be 594 mg/L, the 3 h EC10 was 31.7 mg/L, the 3 h NOEC was 10 mg/L.