Registration Dossier
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EC number: 231-302-2 | CAS number: 7488-55-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Long-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- no glp, no guideline a available (older than guideline and glp) water from lakes was used for experiment; In 1972 water from lakes contained high amounts of chelating agent (e.h. EDTA) Chelating agent stabilze Sn(II) and avoid the formation of hydroxide. So the amount of Sn(II) in water in the study measured is higher than the solubility of Sn(II) at this pH.(see discussion in endpoint summary Environmental fate and pathways)
- Justification for type of information:
- Justification for read across: stannous sulphate and stannous chloride are the salts from strong acids (here: hydrochloric and sulfuric acid) with Sn(II). In water there is a complete dissociation in the Sn(II) and the corrospondenting acid.
In the study water phase the concentration of chloirde and sulfate from natural sources is dimension granter than from the test item. So the chloirde and the sulfate is insignificant. For adverse effects only the Sn(II) is responsible
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 972
- Report date:
- 1972
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 211 (Daphnia magna Reproduction Test)
- Deviations:
- not applicable
- Principles of method if other than guideline:
- For chronic studies five daphnia 12 +/- 12 hr old were placed in 200 ml water in a 250 ml beaker. Four beakers (the test chambers) were used with total 20 animals for each experimental and control condition for each test. The test chambers were covered wirh a pane glase to minimize evaporation, and distributed randomly on a shelf in a constant temperature (18°C +/- 1) Young daphnia were placed in the test chambers, transferd into a new medium at the beginning of each week with a medicine dropper, an subjected to test conditions for 3 wks. Surival of the initial animals was noted after 1, 2 and 3 wks. At the end of the week 3 the surival animals was weighed and prepared for protein and GOT analyses. Reproduction was accessed by counting the young produced every week; the young was counted and discarded each time the inital animals were transfered and at the end of each experiment
- GLP compliance:
- no
Test material
- Reference substance name:
- Tin dichloride
- EC Number:
- 231-868-0
- EC Name:
- Tin dichloride
- Cas Number:
- 7772-99-8
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 3 wk
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 3 wk
- Dose descriptor:
- other: Chronik, 16% reproductive impairment
- Effect conc.:
- 0.35 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- reproduction
- Remarks on result:
- other: value for Sn2+
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.18 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- dissolved
- Remarks:
- Sn
- Basis for effect:
- reproduction
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The value for 16% reproductive impairment was determinated to be 0.35 mg Sn^{+2} /L = 0.63 mg SnSO_4 / L
NOEC(21d)=0.18mg/L
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