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Toxicological information

Epidemiological data

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Administrative data

Endpoint:
epidemiological data
Type of information:
other: Epidemiology
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Assessed by OECD.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Unnamed
Year:
1988
Reference Type:
publication
Title:
Dietary intakes of pesticides, selected elements, and other chemicals: FDA total diet study, june 1984-april 1986.
Author:
Gunderson EL
Year:
1995
Bibliographic source:
J. Assoc. Off. Anal. Chem. 78(4), 910-921
Reference Type:
publication
Title:
FDA Total Diet Study, July 1986-April 1991, Dietary Intakes of Pesticides, Selected Elements, and Other Chemicals
Author:
Gunderson EL
Year:
1995
Bibliographic source:
J Assoc Off Anal Chem 78(6), 1353-1365

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Triphenyl phosphate
EC Number:
204-112-2
EC Name:
Triphenyl phosphate
Cas Number:
115-86-6
Molecular formula:
C18H15O4P
IUPAC Name:
triphenyl phosphate

Method

Details on study design:
This total diet study evaluated chemical contaminants in foods/diets eaten by 8 different age groups of people in the US. More than 200 foods were analyzed and an average diet was determined for 6-11 month olds, 2 year olds, 14-16 year old males, 14-16 year old females, 25-30 year old females, 25-30 year old males, 60-65 year old males and 60-65 year old females. About 105 chemical contaminants were identified including TPP.
Exposure assessment:
estimated

Results and discussion

Any other information on results incl. tables

The calculated intake of TPP in each of the 8 age
groups, in mg/kg body weight/day was: 6-11 month olds - 0.3,
2 year
olds - 4.4, 14-16 year old males - 1.2, 14-16 year old
females - 1.6, 25-30 year old males - 1.6, 25-30 year old
females - 0.8, 60-65 year old males - 0.5 and 60-65 year old
females - 0.5.

These levels were considered safe.

Applicant's summary and conclusion

Executive summary:
This total diet study evaluated chemical contaminants in foods/diets eaten by 8 different age groups of people in the US. More than 200 foods were analyzed and an average diet was determined for 6-11 month olds, 2 year olds, 14-16 year old males, 14-16 year old females, 25-30
year old females, 25-30 year old males, 60-65 year old males and 60-65 year old females. About 105 chemical contaminants were identified including TPP.

The calculated intake of TPP in each of the 8 age
groups, in mg/kg body weight/day was: 6-11 month olds - 0.3,
2 year
olds - 4.4, 14-16 year old males - 1.2, 14-16 year old
females - 1.6, 25-30 year old males - 1.6, 25-30 year old
females - 0.8, 60-65 year old males - 0.5 and 60-65 year old
females - 0.5.

These levels were considered safe.