Registration Dossier
Registration Dossier
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EC number: 941-364-9 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Aquatic / sediment bioaccumulation:
Substance is a hydrocarbon UVCB. Standard tests for this endpoint are intended for single substances and are not appropriate for this complex substance. However, the bioconcentration factor (BCF) values of representative constituents of registration substance has been estimated using BCFBAF model, which uses methodology described by Arnot-Gobas et al. (2003, 2006, 2008). The estimated BCF values of representative constituents range from 3.16 to 19,055 L/kg ww and 0.42 to 1,411 L/kg ww Regression based estimation and Arno-Gobas method (upper trophic) (5% lipid normalisation), respectively. The predicted BCFs for hydrocarbons are generally overly conservative since biotransformation is not quantitatively taken into account. Therefore, indirect exposure and resulting risk estimates predicted by PETRORISK are likely to be overestimated.
QSAR predictions of bioaccumulation of VHGO have also been provided to support the read-across from VHGO to registration substance.
Terrestrial bioaccumulation:
Substance is a hydrocarbon UVCB. Standard tests for this endpoint are intended for single substances and are not appropriate for this complex substance. However, this endpoint has been calculated for representative hydrocarbon structures using default algorithms in the EUSES model as input to the hydrocarbon block method incorporated into the PETRORISK model. The predicted BCFs for hydrocarbons are generally overly conservative since biotransformation is not quantitatively taken into account. Therefore, indirect exposure and resulting risk estimates predicted by PETRORISK are likely to be overestimated.
For purposes of PBT assessment, the substance has been assessed using a combination of QSAR predictions and confirmatory experimental testing for representative constituents using a hydrocarbon block approach. For details see report titled 'Evaluation of PBT for Petroleum Substances' in IUCLID section 13.
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