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Registration Dossier
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EC number: 229-347-8 | CAS number: 6484-52-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Exposure-related observations were described in several reports. These reports showed that after ingestion of ammonium nitrate no occurrences of severe toxicity were observed. Also no measurable hematological effect, elevation of methemoglobin or circulating N-nitroso compounds were observed.
Additional information
- No significant excess was observed for all causes of mortality or for mortality from any of five broad categories of cause or from four specific types of cancer. This was true for the entire cohort as well as for a subgroup that had been heavily exposed to nitrates.
- Direct ingestion of ammonium nitrate cold packs resulted in no occurrences of severe toxicity, although some patients experienced symptoms of gastritis, slight methemoglobinemia, and mild hypertension.
- No measurable hematological effect, elevation of methemoglobin or circulating N-nitroso compounds were observed. Also, no volatile N-nitrosamines were detected in the blood.
- There is no evidence that methaemoglobinaemia is caused by bacterially sound water supplies at concentrations up to 100 mg nitrate.
- Twelve humans resulted in an average urinary nitrate excretion of 75% within 24 h, with small amounts of nitrite detected in only 26% of the samples. Nitrate baseline levels in urine were 149-577 mg/L.
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