Registration Dossier
Registration Dossier
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EC number: 229-347-8 | CAS number: 6484-52-2
Carcinogenicity
Administrative data
- Endpoint:
- carcinogenicity, other
- Remarks:
- not specified
- Type of information:
- not specified
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Mortality of nitrate fertilizer workers
- Author:
- Al-Dabbagh, S., Forman, D., Bryson, D., Stratton, I. and Doll, R.
- Year:
- 1 986
- Bibliographic source:
- British Journal of Industrial Medicine. 43:507-515.
- Reference Type:
- publication
- Title:
- Effect of nitrate and nitrite in drinking water in rats.
- Author:
- Chow, C.K., Chen, C.J. and Gairola, C.
- Year:
- 1 980
- Bibliographic source:
- Toxicology Letters. 6:199-206.
- Reference Type:
- publication
- Title:
- Nitrates, nitrites and gastric cancer in Great Britain.
- Author:
- Forman, D., Al-Dabbagh, S. and Doll, R.
- Year:
- 1 985
- Bibliographic source:
- Nature. 313(6004):620-625.
- Reference Type:
- publication
- Title:
- Nitrates in drinking water and cancer.
- Author:
- Leclerc, H., Vincent, P. and Vandevenne, P.
- Year:
- 1 991
- Bibliographic source:
- Bull. Acad. Natl. Med. 175(4):651-666.
- Reference Type:
- publication
- Title:
- Nitrosamines as environmental carcinogens.
- Author:
- Lijinsky, W. and Epstein, S.S.
- Year:
- 1 970
- Bibliographic source:
- Nature 225(227):21-23. nitroso compounds. Adv. Cancer Res. 10:163-264.
- Reference Type:
- publication
- Title:
- Environmental cancer risks – real and unreal.
- Author:
- Lijinsky, W
- Year:
- 1 989
- Bibliographic source:
- Environmental Research 50:207-209.
- Reference Type:
- publication
- Title:
- Carcinogenic nitroso compounds.
- Author:
- Magee, P.N. and Barnes, J.M.
- Year:
- 1 967
- Bibliographic source:
- Adv. Cancer Res. 10:163-264.
Materials and methods
- Principles of method if other than guideline:
- No data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- nitrates
- IUPAC Name:
- nitrates
Constituent 1
Test animals
- Species:
- other: No data
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- other: no data
- Type of inhalation exposure (if applicable):
- not specified
- Vehicle:
- not specified
- Duration of treatment / exposure:
- no data
- Frequency of treatment:
- no data
- Post exposure period:
- no data
- No. of animals per sex per dose:
- no data
Results and discussion
Any other information on results incl. tables
no data
Applicant's summary and conclusion
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