Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
epidemiological data
Type of information:
other: medical surveillance
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
significant methodological deficiencies
Remarks:
This is a medical surveillance study not an epidemiological study with limited number of subjects.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1977

Materials and methods

Study type:
other: medical surveillance
GLP compliance:
not specified

Test material

Constituent 1
Details on test material:
Purity of test material not reported

Method

Details on exposure:
Chemical Name: Chloropropyltrimethoxysilane
Number of Years Exposed: 17
Average Time Exposed: 6 

Results and discussion

Results:
The results of these studies revealed no major abnormalities. Occasional minimal variations from "normal" were noted but these variations were at random intervals and were not consistent nor persistent.

Applicant's summary and conclusion

Conclusions:
The study did not reveal any harmful effects in the parameters studied in the individuals who were involved in the study.