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Environmental fate & pathways

Biodegradation in water: screening tests

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biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
GLP compliance:
yes (incl. QA statement)
Oxygen conditions:
Inoculum or test system:
activated sludge, domestic, non-adapted
Duration of test (contact time):
28 d
Initial conc.:
117 mg/L
Based on:
Parameter followed for biodegradation estimation:
O2 consumption
Reference substance:
benzoic acid, sodium salt
Key result
% degradation (O2 consumption)
< 5
Sampling time:
28 d
Results with reference substance:
Sodium benzoate (the reference substance) attained a maximum level of biodegradation (based on the BOD:ThOD ratio) of 83%.
The results obtained from the toxicity control bottles showed the test substance did not inhibit the biodegradation of sodium benzoate, as the mean oxygen consumption in the toxicity control bottles was similar to the total of the mean oxygen consumptions by the two separate components.
Validity criteria fulfilled:
Interpretation of results:
under test conditions no biodegradation observed

Description of key information

Under aerobic conditions < 5% biodegradation of HFO-1234yf was observed after 28 days 

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed
Type of water:

Additional information

HFO-1234yf is not found readily biodegradable after 28 days under aerobic conditions.