2-[(2-[2-(dimethylamino)ethoxy]ethyl)methylamino]ethanol

Boiling point

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2003-02-26 to 2003-06-05

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

GLP compliance:

yes (incl. QA statement)

Remarks:

Report represents data generated in the “spirit of” Good Laboratory Practice. GLP deviations were that a Study Plan was not written, however Study-Specific Supplements were provided to study personnel describing laboratory work in detail.

Type of method:

other: thermal analysis

Specific details on test material used for the study:

- Name of test material (as cited in study report): Jeffcat ZF-10, 2-((2-(2-(dimethylamino)ethoxy)ethyl)methyl-amino)-ethanol
- Substance type: Amine
- Physical state: clear colourless liquid
- Analytical purity: 99%
- Lot/batch No.: 324756
- Storage condition of test material: 22 °C in the dark

Key result

Boiling pt.:

263 °C

Atm. press.:

101.8 kPa

The observed duplicate boiling points of ethylene carbonate were 245 °C and 249 °C (at 101.1 kPa). The average 247 ± 2 °C was not significantly different from the reported BP of 248 °C at 101.3 kPa, indicating the method accuracy in this temperature/pressure region was acceptable.

Conclusions:

The boiling point was determined to be 263°C at 101.8 kPa.

Reference 2

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

1990-05-14 to 1990-07-03

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted according to BS4591: 1971 described in EEC Directive 67/548, Annex V, A2. as published in 84/449/EEC. Study follows GLP. Study methods similar to OECD guideline 103

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Version / remarks:

BS4591: 1971 described in EEC Directive 67/548, Annex V, A2. as published in 84/449/EEC.

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

GLP compliance:

yes (incl. QA statement)

Type of method:

distillation method

Specific details on test material used for the study:

- Name of test material (as cited in study report): Texacat ZF-10, 2-[[2-[2-(dimethylamino)ethoxy]ethyl]methylamino]ethanol
- Physical state: Clear colorless liquid
- Analytical purity: 97%
- Lot/batch No.: 90/329
- Expiration date of the lot/batch: Approximately two years from receipt (received on 30 March 1990)
- Storage condition of test material: Dark at room temperature

Boiling pt.:

>= 255.6 - <= 262 °C

Atm. press.:

ca. 990 mm Hg

Conclusions:

The test substance was found to distil over the range 255.6 - 262.0 degrees C (5 - 98%).

Description of key information

The boiling point was determined to be 263°C at 101.8 kPa according to the OECD guideline 103 performed by BC Research Inc. (2003). The study was considered to be reliable without restrictions (Klimisch 1).

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

263 °C

Additional information

The result was supported by another study from 1990 performed under GLP conditions and according to a similar method to OECD guideline 103 reporting a boiling point range of 255.6 - 262.0 °C (5 - 98%).