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Physical & Chemical properties

Vapour pressure

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Description of key information

Vapour pressure: 530 Pa at 25°C (OECD 104)

Key value for chemical safety assessment

Vapour pressure:
530 Pa
at the temperature of:
25 °C

Additional information

A measured vapour pressure of ~400 Pa and 530 Pa at 20°C and 25°C respectively were determined for the substance using the static method (ebulliometer) in accordance with OECD 104. The result is considered reliable and selected as key study. This result is supported by a measured vapour pressure of 130 Pa, 210 Pa and 1590 Pa at 20°C, 25°C and 50°C respectively which was determined for the substance using the dynamic method in accordance with OECD 104 (Haas 2012). Similarly, a predicted vapour pressure of 330 Pa at 25°C was determined for the substance using a validated QSAR estimation method. In other secondary sources to which no reliability could be assigned, vapour pressure values of 517 Pa and 535 Pa at 25°C were reported for the substance.

In another study (Baltussen 2012), vapour pressure values of 1100 Pa and 1900 Pa at 20°C and 25°C respectively (extrapolated) were determined for the substance using an isothermal TGA effusion method in compliance with GLP. The method has been used to measure pressures significantly above the recommended upper limit of 1 Pa for effusion methods in OECD 104, however within a valid upper limit of 1000 Pa reported in the study (based on a laboratory validation process). The result from this study is higher than other available data for octamethyltrisiloxane at ambient temperature, but probably within experimental error. Due to these uncertainties and the availability of other data at 25°C, this result is not considered as key study.

The key study was selected because there are more data points in the study report which crosses ambient temperature with an excellent regression statics.