Registration Dossier
Registration Dossier
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EC number: 203-933-3 | CAS number: 112-07-2
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Valid studies only reported:
P putida, 17hr EC10=722mg/l, EC50=964mg/l
Sewage micro-organisms, 3 hr EC50>1000mg/l, IC50=2800mg/l
Key value for chemical safety assessment
- EC50 for microorganisms:
- 964 mg/L
- EC10 or NOEC for microorganisms:
- 720 mg/L
Additional information
A guideline study using activated sludge respiration inhibition as a measure of toxicity to micro-organisms showed an EC20 of >=900mg/l. In a guideline study where basic details were reported, the bacteria P. putida were exposed to 2 -butoxyethyl acetate to concentrations in excess of 1g/l. The study concluded a 17hr EC50 of 964mg/l and an EC10 (which can be considered a NOEC) of 720mg/l. In a bacterial growth inhibition test using sewage microorganisms and turbimetry as the end point, the substance was found to inhibit growth by 50% at a concentration of 2800mg/l (IC50 =2800mg/l). It can be concluded that the substance has relatively low toxicity to bacteria.
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