Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Recent, well documented study published in open literature

Data source

Reference
Reference Type:
publication
Title:
Higher prevalence of breathlessness in elderly exposed to indoor aldehydes and VOCs in a representative sample of French dwellings
Author:
Bentayeb M, Billionnet C, Baiz N, Derbez M, Kirchner S, Annesi-Maesano I
Year:
2013
Bibliographic source:
Respiratory Medicine 107, 1598-1607

Materials and methods

Endpoint addressed:
other: breathlessness
Principles of method if other than guideline:
To determine the respiratory effects of indoor exposures to aldehydes and VOCs, including butoxyethanol, as objectively measured using passive samplers, in elderly living in a population-based representative sample of French dwellings.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-butoxyethyl acetate
EC Number:
203-933-3
EC Name:
2-butoxyethyl acetate
Cas Number:
112-07-2
Molecular formula:
C8H16O3
IUPAC Name:
2-butoxyethyl acetate

Method

Ethical approval:
not applicable
Exposure assessment:
measured
Details on exposure:
TYPE OF EXPOSURE: Indoor air.

TYPE OF EXPOSURE MEASUREMENT: Area air sampling. VOCs were collected onto Carbograph four adsorbents (Radiello, Fondazione Salvatore Maugeri (FSM)). Adsorbed VOCs were extracted through thermodesorption and analyzed by GC/FID-MS. 567 dwellings were assessed.

Results and discussion

Results:
No measurements of 2-butoxyethyl acetate were detected above the LoD (0.3ug/m3).

Applicant's summary and conclusion

Executive summary:

In a study to measure the levels of indoor air concentrations of a number of volatile organic compounds, 2 -butoxyethyl acetate was not detected.