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Dissociation constant

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Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 112 (Dissociation Constants in Water)
GLP compliance:
no
Dissociating properties:
yes
pKa:
3.19
Remarks on result:
not measured/tested
Remarks:
Temperature not known
Conclusions:
The pKa of the test substance is 3.19
Executive summary:

The pKa of the test substance is 3.19

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Qualifier:
no guideline followed
Principles of method if other than guideline:
No details reported
GLP compliance:
no
Remarks:
published handbook
Dissociating properties:
yes
pKa:
3.17
Temp.:
25 °C

No additional results

Conclusions:
The pKa of hydrofluoric acid (aqueous ) is reported to be 3.17
Executive summary:

The pKa of hydrofluoric acid (aqueous ) is reported to be 3.17

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Qualifier:
no guideline followed
Principles of method if other than guideline:
Measurement of dissocitation constant using the indicator technique
GLP compliance:
no
Remarks:
published literature study
Dissociating properties:
yes
pKa:
3.14
Temp.:
25 °C
Remarks on result:
other: Atmospheric pressure

A pKa of 3.14 was obtained by extrapolation to zero ionic strength at 1 atm

Conclusions:
The pKa for hydrofluoric acid at atmospheric pressure was reported to be 3.14
Executive summary:

The effect of pressure on the dissociation constant of hydrofluoric acid was determined using the indicator technique, at 25°C at an ionic strength of 0.1 M over a pressure range of 1 to 2000 atm. A value of 3.14 for pka at I =0 was obtained by extrapolation to zero ionic strength at 1 atm.

Description of key information

The pKa of the substance is reported to be 3.19 (Merck Index), 3.14 (Usha & Atkinson, 1992) and 3.17 (Speight, 2005)

Key value for chemical safety assessment

pKa at 20°C:
3.19

Additional information

The pKa of the substance is reported to be 3.19 (Merck Index), 3.14 (Usha & Atkinson, 1992) and 3.17 (Speight, 2005)