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Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only summary data provided with limited information on methods and results.
Cross-reference
Reason / purpose:
reference to same study

Data source

Reference
Reference Type:
publication
Title:
Final report on the safety assessment of propylene carbonate
Author:
Beyer KH Jr., Bergfeld WF, Berndt, WO, et al.
Year:
1987
Bibliographic source:
Journal of the American College of Toxicology Vol 6, (1)

Materials and methods

Principles of method if other than guideline:
Acute exposure to concentrated vapours over 8 hours followed by a 14 day observation period.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation: vapour
Type of inhalation exposure:
not specified
Vehicle:
other: no data
Details on inhalation exposure:
Exposure to concentrated vapours for 8 hours
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
8 h
Concentrations:
No data
No. of animals per sex per dose:
6 animals
Control animals:
not specified
Details on study design:
- Duration of observation period following administration: 14 days

Results and discussion

Mortality:
Not lethal

Applicant's summary and conclusion