Registration Dossier
Registration Dossier
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EC number: 201-143-3 | CAS number: 78-79-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The 5 day NOEC is 2 mg/L. TLM QSAR was used to calculate EL50 of isoprene towards activated sludge. The calculated EL50 is 262.105 mg/L.
The lowest value was used for chemical safety assessment.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 2 mg/L
Additional information
Huntingdon Life Sciences (2003) investigated the toxicity of isoprene to microorganisms as part of an OECD TG 301D biodegradation screening test. The biodegradation of sodium benzoate both in the presence of and without isoprene was studied. Huntingdon Life Sciences found that isoprene was not inhibitory to the biodegradation of sodium benzoate at the concentration tested. Therefore, isoprene is not considered inhibitory to microorganisms at 2 mg/L.
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