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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1992-03-25 to 1992-04-22
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study in accordance with OECD TG 105
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
column elution method
Key result
Water solubility:
8.8 mg/L
Temp.:
20 °C
pH:
>= 6.8 - <= 7.1
Details on results:
The test was performed with two columns and the measured concentration was 8.9 mg/L in column 1 and 8.6 mg/L in column 2.
Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
Solubility of benzyl salicylate in water at 20°C is 8.8mg/l.
Executive summary:

The water solubility of the test substance was determined under GLP according to the column elution method described in OECD TG 105. The test was performed in parallel with two columns. The inert material in the columns was Chromosorb W/AW with a particle size of 0.15 to 0.18 mm. The test temperature was 20 °C ± 0.5 °C. The concentration of the test substance in the eluate was measured by HPLC analysis. The mass concentration in the eluates of column 1 and 2 was 8.9 mg/L and 8.6 mg/L. The average water solubility determined in this study was 8.8 mg/L at 20 °C.

Description of key information

Water solubility was determined to be 8.8 mg/L at 20 °C in accordance with OECD guideline 105 using the column elution method.

Key value for chemical safety assessment

Water solubility:
8.8 mg/L
at the temperature of:
20 °C

Additional information

The water solubility of the test substance was determined under GLP according to the column elution method described in OECD TG 105. The test was performed in parallel with two columns. The inert material in the columns was Chromosorb W/AW with a particle size of 0.15 to 0.18 mm. The test temperature was 20 °C ± 0.5 °C. The concentration of the test substance in the eluate was measured by HPLC analysis. The mass concentration in the eluates of column 1 and 2 was 8.9 mg/L and 8.6 mg/L. The average water solubility determined in this study was 8.8 mg/L at 20 °C.