Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-474-9 | CAS number: 107-22-2
Endpoint summary
Administrative data
Description of key information
Additional information
Soil macroorganisms:
Effects of Glyoxal 40% on mortality and biomass development of the earthwormEisenia fetidawere studied in a 14-d acute study following OECD TG 207. Based on nominal concentrations, the 14 -d LC50 was > 398 mg a.i./kg soil dw (BASF, 2009; report No. 67E0496/013033). Normalized to standard soil with 3.4% organic matter content, this corresponds to > 135 mg a.i./kg soil dw.
Terrrestrial plants:
With glyoxal 40% a seedling emergence and seedling growth study according to OECD 208 was performed with three plant species (Avena sativa, Brassica napus, Vicia sativa) under GLP (BASF SE, 2009; report No. 65E0496/013029). Results with the most sensitive species Brassica napus and Vicia sativa revealed an EC50 of >400 mg a.i./kg dw soil and a NOEC of 203.2 mg a.i./kg dw soil. Corrected for 3.4% standard soil organic matter content, this corresponds toEC50of > 618mg a.i./kg dw soil, a NOEC of 314 mg a.i./kg dw soil and a LOEC of 618 mg a.i./kg dw soil.
Soil microorganisms:
The toxicity of Glyoxal 40% to soil microorganisms was tested in two GLP guideline studies following OECD TG 216 and 217, respectively.
In the OECD 216 study, effects on nitrogen transformation were not observed up to 400 mg a.i./kg soil dw. The EC10 and the EC50 were both > 400 mg a.i./kg soil dw (BASF 2009; report No. 37G0496/013026). Normalizing to 3.4% standard soil organic matter content, this corresponds to EC10 and EC50 > 1054 mg a.i./kg soil dw.
In the OECD 217 study, the EC50 for effects on carbon transformation/soil respiration was also > 400 mg a.i./kg soil dw. The EC10 was 240 mg a.i./kg soil dw (BASF 2009; 38G0496/013025). Normalizing to 3.4% standard soil organic matter content, this corresponds to an EC50 > 1054 mg a.i./kg soil dw, and EC10 = 633 mg a.i./kg soil dw.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
