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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Description of key information

No effects up to the limit of water solubility (< 0.05 mg/L) based on available data (OECD 211).

Key value for chemical safety assessment

Additional information

Since no studies investigating the effects of fatty acids, coco, isotridecyl esters (CAS 91031-91-3) are available for this endpoint, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read-across to the structurally related category member Fatty acids, C8 - 10, C12 - 18-alkyl esters (CAS 95912-86-0) was conducted. This read-across is justified in detail in the overall summary (IUCLID Section 6.1) and within the category justification in IUCLID Section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance was used for the assessment. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance was used for the assessment. Fatty acids, C8 - 10, C12 - 18-alkyl esters is characterized by similar fatty acid (C8-C10 compared to C12-C14 (target)) and fatty alcohol (C12-C14 compared to C13 (target)) chain lengths. As it can be seen in the data matrix of the category justification in section 13 and the overall summary, all reliable data in the category support the hazard assessment of each category member by showing a consistent pattern of results.

The study with the read-across substance fatty acids, C8-10, C12-18-alkyl esters (CAS 95912-86-0) was performed according to OECD 211 (GLP) (Salinas, 2013). Daphnia magna was exposed to a nominal loading rate of 10 mg/L (Water Accommodated Fraction). Chemical analysis of the test substance concentrations was not possible since no suitable analytical method could be developed to detect the test substance. No effects on reproduction of D. magna were observed up to the water solubility limit (< 0.05 mg/L) resulting in a NOELR (21 d) ≥ 10 mg/L. Based on the available results from one structurally related read-across substance (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) which is characterized by a similar ecotoxicological profile and comparable structure, it can be concluded that fatty acids, coco, isotridecyl esters will not exhibit long-term effects to aquatic invertebrates up to the limit of water solubility.

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