Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Neurotoxicity

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Administrative data

Description of key information

The toxicology of sulphuric acid has been adequately described. The hazards associated with its corrosive or irritant nature (depending on the dilution) are known, and appropriate risk and safety phrases are in place.  The immediate dissociation to hydrogen and sulphate ions in water, and the ubiquitous nature of both of those ions in physiological processes render further testing unnecessary.

Key value for chemical safety assessment

Effect on neurotoxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Effect on neurotoxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Effect on neurotoxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

The toxicology of sulphuric acid has been adequately described. The hazards associated with its corrosive or irritant nature (depending on the dilution) are known, and appropriate risk and safety phrases are in place. The dissociation to hydrogen and sulphate ions in water coupled with the ubiquitous nature of both of those ions in physiological processes render further testing unnecessary.


Justification for selection of effect on neurotoxicity via oral route endpoint:
A waiver is presented for this endpoint

Justification for selection of effect on neurotoxicity via inhalation route endpoint:
A waiver is presented for this endpoint

Justification for selection of effect on neurotoxicity via dermal route endpoint:
A waiver is presented for this endpoint

Justification for classification or non-classification