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Toxicity to microorganisms

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Description of key information

Fatty acids, C16-18, esters with pentaerythritol (CAS-No. 85116-93-4) is not harmful to microorganisms.

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Two studies, investigating the short-term toxicity to Pseudomonas putida once of 2,2-bis[[(1-oxoisooctadecyl)oxy]methyl]-1,3-propanediyl bis(isooctadecanoate) (CAS-No. 62125-22-8) and once of Pentaerythritol tetraoleate (CAS-No. 19321-40-5), were used as read across for Fatty acids, C16-18, esters with pentaerythritol (CAS-No. 85116-93-4). These substances are structurally and composition related to Fatty acids, C16-18, esters with pentaerythritol (CAS-No. 85116-93-4). Both static GLP-cell multiplication inhibition tests (both: Mead, 1997) according or equivalent to ISO 10712 showed no effect on the growth of P. putida at the tested concentration after 16 hours (EL10/ EL50 > 10000 mg/L, NOELR ≥ 10000 mg/L). A conclusion by analogue approach has been applied. Based on the analogy it can be concluded that no toxicological effects on microorganisms are expected for Fatty acids, C16-18, esters with pentaerythritol (CAS-No. 85116-93-4). Furthermore, the biodegradation tests exhibit the readily biodegradability of the target substance. Therefore, the sensitive single species as well as the activated sludge test shows, inhibition and a disturbance in the biodegradation process of a sewage treatment plant is not anticipated.