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Stability in organic solvents and identity of relevant degradation products

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Description of key information

Not applicable.

Additional information

According to ECHA's "Guidance on information requirements and chemical safety assessment, Chapter R.7a: Endpoint specific guidance", only if the test item's stability in organic solvent is considered critical this type of study would be required. Examples of when stability in organic solvents could be important are given in the same guidance document:

- for certain solubility measurements (e.g. octanol-water partition coefficient)

- to check on the stability of reagent solutions, fortification standards or calibration standards

- when a test substance is dosed as a solution in an organic solvent (e.g. ecotoxicity studies)

- when a test substance is extracted from an environmental sample, plant or animal tissue or diet matrix (arising from a variety of physico-chemical property, ecotoxicity and animal toxicity studies) into an organic solvent and stored pending analytical measurement.

As all these points are deemed to be not applicable to test item, no study on stability in organic solvents is run.