Zinc oxide

Hydrolysis

Link to relevant study record(s)

Reference

Endpoint:

hydrolysis

Data waiving:

study technically not feasible

Justification for data waiving:

other:

Justification for type of information:

According to Annex XI of Regulation 1907/2006, testing for a specific endpoint may be omitted if testing does not appear to be scientifically necessary or if it is technically not possible to conduct the study as a consequence of the properties of the substance. Under REACH (ECHA 2017, Chapter R.7B – Endpoint Specific Guidance), the term ‘Hydrolysis’ refers to the “Decomposition or degradation of a chemical by reaction with water”, and this as a function of pH (i.e., abiotic degradation). In the case of the current substance, the chemical safety assessment will be based on elemental metal concentration. Please refer to section 4.8 on solubility.

The surface treatment applied does not modify the properties of the substance.
This justification applies to both sets of nanos: the "Zinc oxide nano with and without hydrophilic surface treatment" set and the "Zinc oxide nano - hydrophobic surface treatment" set.

Description of key information

According to Annex XI of Regulation 1907/2006, testing for 
a specific endpoint may be omitted if testing does not 
appear to be scientifically necessary or if it is 
technically not possible to conduct the study as a 
consequence of the properties of the substance. Under 
REACH (ECHA 2017, Chapter R.7B – Endpoint Specific Guidance)
, the term ‘Hydrolysis’ refers to the “Decomposition or 
degradation of a chemical by reaction with water”, and 
this as a function of pH (i.e., abiotic degradation). 
In the case of the current substance, the chemical 
safety assessment will be based on elemental metal 
concentration. Please refer to section 4.8 on solubility.