Registration Dossier
Registration Dossier
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EC number: 205-619-1 | CAS number: 144-19-4
Endpoint summary
Administrative data
Description of key information
readily biodegradable |
Additional information
Two ready biodegradation studies have been performed on 2,2,4-trimethylpentanediol (TMPD). The key study was conducted using the DOC Die-Away Test (OECD Guideline 301A). In that study a lag phase of approximately 3 - 4 days occurred before biodegradation reached 10% in both test vessels. The test substance reached 91% and 98% degradation within the subsequent 10-day window. At test end, the test substance showed 99% and 100% degradation (as measured by loss of DOC). In the second study based upon CO2 evolution an average of 87.8% biodegradation was observed within 28 days. Based upon the results of these studies the substance meets the criteria to be considered readily biodegradable.
In addition to the ready biodegradation studies, a wastewater treatment plant simulation study was conducted using a Semi-Continuous Activated Sludge (SCAS) Removability Test. This test is designed to determine the removability of the test substances in the SCAS test system, as measured by soluble organic carbon (SOC). In this study the sludge organisms were incrementally acclimated to TMPD over 7 days followed by a 7 day test period. During the 7 day test period SOC was measured in samples removed from the control and test substance replicates. The volume of sample removed was replaced with a comparable volume of fresh influent containing the test substance and synthetic sewage and the process was repeated each day. The results of these daily analyses over the 7 day test period was a daily mean removal of 101% with a 95% confidence interval of ± 1.6%.
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