Registration Dossier
Registration Dossier
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EC number: 200-838-9 | CAS number: 75-09-2
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
It is considered that hydrolysis is the reaction of a substance with water in which the water molecule or the hydroxide ion displaces an atom or group of atoms in the substance. Therefore, hydrolysis of an organic chemical at a pH normally found in the environment (i. e., pH 5 to 9) can be important for chemicals that have functional groups that are potentially hydrolysable in this pH range, such as alkyl halides, amides, carbamates, carboxylic acid esters and lactones, epoxides, phosphate esters, and sulfonic acid esters.
It is reported that dichloromethane hydrolyses slowly in the presence of water, producing small quantities of hydrogen chloride (WHO, 1996).
The US EPA developed model, HYDROWIN (v. 2.00), was applied to estimate hydrolysis rate of dichloromethane.
Based on the data summarised here, dichloromethane is not expected to hydrolyze appreciably in the environment.
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