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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Exposure related observations in humans: other data

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Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
other information

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Pulmonary responses to purified zinc oxide fume
Author:
Kuschner WG, D'Alessandro A, Wintermeyer SF, Wong H, Boushey HA, Blanc PD
Year:
1995
Bibliographic source:
J Investig Med. 1995 Aug;43(4):371-8.
Reference Type:
secondary source
Title:
No information
Author:
European Chemicals Bureau
Year:
2004
Bibliographic source:
EU Risk Assessment Report: CAS 1314-13-2

Materials and methods

Type of study / information:
inhalation exposure to purified zinc oxide fume (Zn particles <100 nm)
Endpoint addressed:
acute toxicity: inhalation

Test material

Constituent 1
Chemical structure
Reference substance name:
Zinc oxide
EC Number:
215-222-5
EC Name:
Zinc oxide
Cas Number:
1314-13-2
Molecular formula:
ZnO
IUPAC Name:
oxozinc
Details on test material:
- primary particael mean diameter: 8-40nM- mass diameter: 170 nm

Method

Details on exposure:
- mean concentration: 16.4 mg/m3 (2.76-37.0 mg/m3)

Results and discussion

Applicant's summary and conclusion