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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Carcinogenicity

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Administrative data

Description of key information

A 104 week repeated dose study is available in which NaHCO3 was given in combination with o-phenylphenol (OPP-Na). One group received NaHCO3 only (0.64%)

Key value for chemical safety assessment

Justification for classification or non-classification

Based on the available information, the substance does not need to be classified according to CLP Regulation (EC) No 1272/2008.

Additional information

No carcinogenic effects were found in a valid study when male Fischer 344 rats were exposed to sodium bicarbonate alone. There is no evidence of NaHCO3 having carcinogenic effects.

[taken from OECD SIDS on sodium bicarbonate (2002), pg. 18]