Registration Dossier

Diss Factsheets

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
other: Exposure estimation
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
Pennington JAT (1991). Silicon in foods and diets. Food Add.|and Cont. 8(1), 97-118.

Materials and methods

Type of study / information:
Type of experience: Human - Exposure through Food
Principles of method if other than guideline:
Exposure estimation

Test material

Constituent 1
Chemical structure
Reference substance name:
Silicic acid, potassium salt
EC Number:
215-199-1
EC Name:
Silicic acid, potassium salt
Cas Number:
1312-76-1
Molecular formula:
K2O x (SiO2)n with Molar Ratio (MR) (SiO2/K2O): 0.5 – 5 (with exception of MR = 1)
IUPAC Name:
potassium hydroxysilanoylolate

Method

Exposure assessment:
estimated

Results and discussion

Any other information on results incl. tables

The average intake of silicon is 20-50 mg total Si/d (Pennington, 1991). An estimation of 0.31 mg Si/kg bw/d in
females and 0.53 mg Si/kg bw/d in males made in an American study, is representative for the intake in the Western
world. While the highest concentrations of total silicon are found in seafood, eggs and diary products; the main dietary
sources are cereals and beverages.

Applicant's summary and conclusion