2,4,6-trinitrotoluene

Short-term toxicity to fish

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods

Qualifier:

equivalent or similar to guideline

Guideline:

other: Modified U.S. Environmental Protection Agency. 2002. Methods for measuring the acute toxicity of effluents and receiving waters to freshwater and marine organisms, 5th ed. EPA-821-R-02-012. Office of Water, Washington, DC

GLP compliance:

not specified

Test organisms (species):

Pimephales promelas

Test type:

semi-static

Water media type:

freshwater

Total exposure duration:

10 d

Remarks on exposure duration:

(4- and 10-d experiment)

Key result

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

2.7 mg/L

Nominal / measured:

meas. (geom. mean)

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Remarks on result:

other: 95%CL

Sublethal observations / clinical signs:

LC50 (96 h): > 10.29 — 13.83 µmol/L test mat. (meas. (geom. mean)) based on: mortality (95%CL)

Description of key information

In accordance with Regulation EC 1272/2008 (CLP) and based on available data substance can be classified as hazardous to the aquatic environment chronic category 2 as 1 mg/L < LC50 < 10 mg/L and the substance is poorly biodegradable.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish

Dose descriptor:

LC50

Effect concentration:

2.7 mg/L

Marine water fish

Marine water fish

Dose descriptor:

LC50

Effect concentration:

2.7 mg/L