Registration Dossier
Registration Dossier
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EC number: 217-006-6 | CAS number: 1719-57-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Reliable read-across data showed a EC50 (48h) >100 mg/L in a daphnia toxicity study.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
No reliable data is available for Chlor(chloromethyl)dimethylsilane (CAS No. 1719-57-9). The available daphnia study was assigned to Klimsch category 3 due to major procedural deficiencies. However, due to fast hydrolysis read across to the hydrolysis product (Chloromethyl)dimethylsilanol is warranted according to ECHA guidance that states that “for substances where hydrolytic DT50 is less than 12 hours, environmental effects are likely to be attributed to the hydrolysis product rather than to the parent itself."
Hydrochloric acid is not classified for environmental hazards. Data relevant for the assessment of the other hydrolysis product, i.e. (Chloromethyl)dimethylsilanol can be taken from (Chloromethyl)methoxydimethylsilane (CAS#18143-33-4) which shares the same silanol hydrolysis product by fast hydrolysis. The hydrolysis half-life of (Chloromethyl)methoxydimethylsilane has been calculated by a validated QRMF (P.R. Fisk 2013 and 2014) to be 0.6 hours. The other hydrolysis product (methanol) is also not classified for environmental hazards and thus not relevant for the assessment.
For (Chloromethyl)methoxydimethylsilane a reliable daphnia test is available with a EC50 (48h) > 100 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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